These are the Pokemon who can mega evolve in X, Y, Omega Ruby, and Alpha Sapphire:
Venusaur, Charizard, Blastoise, Alakazam, Gengar, Kangaskhan, Pinsir, Gyarados, Aerodactyl, Mewtwo, Ampharos, Scizor, Heracross, Houndoom, Tyranitar, Blaziken, Gardevoir, Mawile, Aggron, Medicham, Manectric, Banette, Absol, Garchomp, Lucario, and Abombasnow.
Only in Pokemon Omega Ruby and Alpha Sapphire:
Beedrill, Pidgeot, Slowbro, Steelix, Sceptile, Swampert, Sableye Sharpedo, Camerupt, Altaria, Glalie, Salamence, Metagross, Latias, Latios, Rayquaza, Lopunny, Gallade, Audino, and Diancie.
These Pokemon are considered Primal and do not fall into the Mega Evolution category completely:
Kyogre and Groudon.
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Have it hold the Sceptilite, then press "Mega Evolution" during a battle to Mega Evolve it.
Mewtwo is the ultimate Psychic type legendary Pokemon. It was introduced in the first generation and does not evolve into any other Pokemon, although as of the sixth generation it can mega evolve into Mega Mewtwo X or Mega Mewtwo Y.
It's mega stone I think is a new item for rayquaza called the green orb
No, because Mega Evolution wasn't introduced until Pokemon X and Y.
Hitmonlee cannot evolve any further, nor does it have a Mega Evolution form.