Most of the time the only difference is the bonuses which are allocated with them that makes the pre-order interesting, as you may notice games does not end out of stock like consoles do and if they do you can always opt with the digital version. which nowadays most gamers do.
So basically the difference is only in what you get with it and not the price. games rarely go up on value after the release date, most of them stay the same and some even go lower on price value.
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Games are preordered at full retail price, but may include bonuses. After a game's release you may find the game discounted and the longer after the release the more likely t will be cheaper than paying full retail.
As an example MW3 is being sold for preorder for full retail price and some small bonus items, but it will likely be available for 25% or more of a discount before the end of November 2011 for the Black Friday/Cyber Monday holiday sales. The same for Black Ops II this holiday season
It really depends upon your plan, pre-ordering a title may cost more, but it is due to the fact that you can get special bonuses like the Halo 3 pre-order bonus that had master chief's helmet as a disc case.
But if you do not plan on getting the bonuses (or if there are none), you can just wait half a year for its retail value to drop, like with Fallout 76.
It is sometimes cheaper to pre-order on Steam, but occasionally publishers will do exclusive deals with certain 'bricks-and-mortar' retailers which allows them to sell it a lot cheaper than Steam can (although this happens the other way round occasionally too).
pre order mean`s your prodoct comes out after the day you order it
Now you can on Amazon, buy it there and you will get it on March 8th
you pre order Nintendo dsi
You have to either pre order it at best buy or get it as a DLC but if you do not have xbox live you cant get it as a DLC