There is no sure way to defeat them at all , just have some good level Pokemon , and a range from Ice , Electric , Ghost , Grass , Fire , Ground and normal , and you will win that way
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you defeat the elite four you defeat the elite four
After you defeat the elite four on Pokemon sapphire you complete the pokedex and make all your Pokemon level 100.
The Elite Four is in the Indigo Plateau.
One island Pokemon centre after you defeat elite four and the 2 rockets at the volcano and find the gem.
You go and have a tug