You cannot "beat" the game, but you can unlock all the cards, duelists, etc. Go to GameSpot.com and look up the game to see all of what you can unlock.
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If you have a deck that needs monsters sent to the graveyard like a lightsworn deck, then you might win.
you can try using exodia or destiny board or you use action replay and gell all cards and infinite life
first you beat the lv four five times then complete 70% of all the challenges this unlocks all of them this includes the duel puzzles, survival. I hope this helps since my friend is telling me what to write happy duelling .
The best card in yugioh is the judegement dragon card.