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Yes, five: Zapdos, Articuno, Moltres, Mewtwo, and ONE of the Johto Legendary Trio (entei, raikou, or suicune) the johto legend depends on the starter you choose. Also, Deoxys, Lugia, and Ho-oh were given away in events.
you find cobalin in mistralation cave, virision in pinwheel forest, and terrakin in victory road
They roam the Sinnoh region after you talk to Professor Oak in Eterna City after getting the National Pokedex.
Raikou, Entei, and Suicune are the legendary dogs. Some consider Arcanine a legendary dog, but he is not part of the trio. the reason for this is that in an early episode, Arcanine was in the middle of a slate surrounded by Moltres, Articuno, and Zapdos. After the episode, it was decided that Arcanine was NOT a legendary dog.
Legendaries dont breed... neither do the legendary dogs, muskateers, elves, birds, dragons, Mew and Mew 2, Victini, or the Kami trio.