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There are currently many people working for Nintendo and making the games and the systems, so yes anyone can work for Nintendo if they have the right education.
All Nintendo DS are region-free, there is no regional lockout. Any Nintendo DS game will work with any Nintendo DS, and any Nintendo DS game is compatible for multiplayer with another Nintendo DS game, of a different country of origin. I DON'T KNOW!!!!!!!
Wii games are region-locked, US games for it will not work on a European console.
All DS games work on both the DS and the DS Lite. Games that require a GBA cartridge slot (like the Guitar Hero games) do not work on the DSi, as the GBA slot has been removed. also dont try 3ds games on any ds ( but 3ds) it wont work but you can play ds games on it :( but not 3d
It is possible to use a smart card with the Nintendo DS to play pirated games. This has been made illegal.