In most cases you can.
Chat with our AI personalities
No. You have to have a guitar (Can be "Rockband" or "Guitar Hero" guitar or a drum set.)
You can play Rock band with a guitar hero guitar, but you can't play Guitar Hero with a Rock Band guitar.
yes but you need the guitar grip to play
no you need the guitar grip
I don't believe you can use the PS3 Guitar Hero controller on the PC to play anything