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in Pokemon : pearl in real life : quartz
no.
in real life you can not go in the Pokemon world but you can pretend.:)
It was thought to be the next Pokemon game, after diamon and pearl. But now, it's been told that Pokemon Platinum will be the next game. So up till now, no Pokemon opal is not a real game.
I don't think that you could make Pokemon real , but wouldn't it be so cool if it was? the first Pokemon i would catch is probably Zorua and simisear