The Beverly Hillbillies was sometimes cagey about pinning down exactly where the Clampetts had lived, usually referring to their home region simply as "the Hills." But it was generally understood to be the Ozarks (Southwestern Missouri and Northwestern Arkansas), specifically the town of Bug Tussle. A series of episodes around the middle of the run of the series saw the Clampetts returning to Silver Dollar City, which was (at the time) a new theme park near Branson, though it was treated as an actual town on the show. One of the preliminary titles of Petticoat Junction, a spinoff of The Beverly Hillbillies set near the Clampetts' original home, was Ozark Widow.
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The Beverly Hillbillies - Season 1 Episode 1 - The Clampetts Strike Oil
Jefferson Davis Clampett
It is never explicitly stated in the series what state the Clampetts moved from, but several references to towns and counties indicate they were from the Ozarks, so they probably came from either Missouri or Arkansas.
The Clampetts from "The Beverly Hillbillies". Jed Clampett lived with his daughter Elly May, his mother-in-law "Granny" Daisy Moses, and his cousin's son Jethro Bodine.
While never clearly defined, it would appear- in line with Hollywood tradition that the Clampetts hailed from a backward region such as the Ozarks. Hillbillies implies mountainous terrain. The basic plot was overloaded with impossibilities- implausibilities and non-sequiturs, an essentially thirties plot ( including the old time truck)- updated to the fifties and sixties ( and modern cars shown) it just was- well impossible.