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Tsunade wakes up in episode 219 just when Kakashi Hatake is about to become the sixth hokage.

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More answers

Tsunade Going to wake up just as kakkashi is about to Be the six hokage but as she has woke up kakkashi does not need to be hokage and tsunade is still the 5th hokage. Then the others hokage holds hokage summit where tsunade gets filled in whats happening and at the hokage summit she agrees to send naruto away for his his own safety.

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Wiki User

13y ago
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Whilst Naruto is fighting Pain, Tsunade gets knocked into a coma for she has reduced almost all her chakra. Naruto then defeats Pain then Danzou becomes Hokage until he dies by Sasuke then Tsunade wakes up and becomes Hokage again.

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Wiki User

14y ago
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Watch and see, and then come back and answer.

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Wiki User

17y ago
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In Naruto shippuden episode 219

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Wiki User

13y ago
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yes tsunade does wake up

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Anonymous

4y ago
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Q: When does tsunade wake up?
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