Sasuke loses it in his fight with Itachi when they are fighting and orochimaru emerges from Sasuke in the form of a 8 headed snake and itachi uses the sword of totsuka to seal orochimaru for all eternity along with the curse mark.
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Now there is only two, and their names are Sasuke and Madara
Kimimaro's curse mark is the seal of heaven, just like Sasuke's
Itachi removed it and killed Orochimaru during his fight with sasuke.
No. Sasuke will be freed from his curse mark when he fights Itachi. Itachi actually loves Sasuke. He had to destroy his clan because the Uchiha clan was planning to bring chaos. He killed everyone but he could not kill Sasuke. Itachi was planning to make Sasuke a great ninja, so, he acted as if he hated Sasuke so that Sasuke will train and grow stronger then himself. When Sasuke fought Itachi, Itachi was the one who released him from the curse mark. Sadly, Sasuke kills Itachi in the same battle not knowing the truth of his brother that has been lying to Sasuke all this time. Actually, Itachi seals Orochimaru with the Totsuka Blade (the blade of sealing) with Susano o' and the curse mark is gone.
Yes. He gets rid of the curse mark when he fights itachi for the last time.