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There are quite a few.
The movie Ed Gein was based on the serial killer Ed Gein. The Texas Chainsaw Massacre was also inspired by him.
The movie The Exorcist is also based on a true story. And so forth.
If you are looking for a specific movie, please post the question again and provide more details in your question.
"To Catch a Killer" (1992). About the serial killer John Wayne Gacy. Stars Brian Dennehy, Margot Kidder, Meg Foster.
"In Broad Daylight" (1991). Stars Brian Dennehy, Cloris Leachman, Marcia Gay Harden. A family terrorizes a small town.
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