No she hasn't have a grandchild ,cause she even married yet.
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=No, but naruto calls her grandma tsunade just to annoy her.=
Yes. He has a grandson named Sean that is 20 this year.
Well hard to say at this point. Danzo was made the sixth but he was killed....i guess that meens kakashi would prob be the 7th hokage, making naruto the 8th, this is all observation. Danzo wasnt rly hokage very long, so if kakashi was called the 6th since danzo died like 8 episodes into him being hokage, naruto would prob be the 7th, and im guessing its likely Komahomaru would be after naruto since hes the 3rd hokage's grandson....unlikely the series will go that far though.
Not his grandson, but they are distant relatives.
Naruto vs. Haku, Naruto vs. Orochimaru, Naruto vs. Kimimaru, Naruto vs. Sasuke, Naruto vs. Deidara/Sasori, Naruto vs. Orochimaru, Naruto vs. Pain.