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Technically, yes, they are related, though remotely, because the Uzumaki clan is distantly related to the Senju clan. Naruto's descendancy from the Uzumaki clan and Tsudnade's being the granddaughter of the First Hokage, from the Senju clan, makes them distantly related.

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14y ago

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Yes because Tsunade's grand mother Mito Uzumaki is the great great great grand mother of naruto

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13y ago
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Q: Is naruto related to Tsunade
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