no!. its tsunade grandfather
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Naruto's grandfather is hashirama senju because kushina ( naruto's mother) is the daughter of hashirama senju. so basicly hashirama senju is naruto's grandfather.
Uchiha Madara and Senju Hashirama
Starting from the left there is1st Hokage (Hashirama Senju)2nd Hokage (Tobirama Senju)3rd Hokage (Hiruzen Sarutobi)4th Hokage (Minato Namikaze)5th Hokage (Tsunade)(There is also a 6th Hokage named Danzo but his face is not carved in the Hokage Monument.)
Kin Tsuchi dies in Naruto episode 69- Village in Distress: A New A-Ranked Mission! when Orochimaru sacrifices she and Zaku Abumi to use Summoning: Impure World Resurrection to summon the First and Second Hokage (Hashirama Senju and his brother Tobirama Senju) to battle against the 3rd Hokage (Hiruzen Sarutobi).
No, he isn't a direct decendant.