Nobody knows. That information hasn't been revealed yet.
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No, Madara does not die.... at all. Madara (aka Tobi) is immortal, so therefore he does not die. ;)
He had at least five brothers. Four were killed in battle, when Madara was still a child. He also had a younger brother, Izuna Uchiha.
The author never revealed if Madara Uchiha married anyone.
There is no "Last Survivor of the Uchiha Clan", but there are "Last Survivors of the Uchiha Clan" whom are Madara Uchiha and Sasuke Uchiha. Although the "Last Survivor of the Uchiha Clan" is most likely to be Madara after Sasuke dies since Madara will live eternally, according to fan predictions. Madara,Sasuke and Itachi.....now only Sasuke,but the other 2 are also revived by edo tensei
Madara Uchiha is a man.