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Not sure what you mean by "an eye problem." There is no information online about her having an eye injury or eyesight issues.
He lost his vision in his right eye due to amblyopia since he was young
He burst the blood vessels in his eye from the strain of weight training
If you're asking why his eye is like that,in a his interview he said about that he did not to his eyes or soemthing.It happened to him when he was born.It's something about his muscle of his eyelid.And if you think oh okay one eye is half closed but another one is completely opened so much , he says that he tried to open it as he could to see well.
he didnt lose it,he wore a scope on his left eye for long-range observation, and he had trained the eye itself to counter genjutsu, allowing him to see through and negate them. This was done in response to Itachi's powerful genjutsu skills, of which he had a considerable loathing, and wished to defeat if he got the chance. yeah and in the fight against sasuke he takes the scope off.