Orochimaru did not love anyone but in their past it seemed like Tsunade had a crush on him. Also Jirya had a crush on Tsunade kind of like how Naruto has a crush on Sakur. And No they are not Cousins at all. They were team members along with Orochimaru who were known as the legendary Sannin
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Orochimaru Nikameto Tsunade Senju Jiraya Fosintao
Orochimaru, Tsunade and Jiraya
She resembles Tsunade. And orochimaru was on the same team as she was.
lol the question says what episode does jiraiya and tsunade fight orochimaru, and its 52 not 133, 133 when naruto and sasuke fought
naruto because if you watch the beginning of shippuden you will see that naruto almost killes orochimaru