I believe the term "locked-in syndrome" refers to when a celebrity is under house arrest.
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Yes, as a matter of fact several come to mind. Monty Hall the MC of "lets Make A Deal" has Crohns disease as does Mike McCready of Peal Jam, Shannon Daugherty of 90210 and the late Curt Cobain of Nirvana.
As celebrities rarely give out their IQs, we will probably never know the answer to this. However, we may assume that it is someone with a recognized developmental delay such as Down syndrome or diagnosed developmental delay.
Only invite over the celebrities whom you know personally. Celebrities do not accept invitations from strangers.
Crouzon syndrome
Some of the celebrities who celebrate on May 28th are Kylie Minogue, Elizabeth Filarski, and John Fogerty. See the link for more celebrities.