No, they are not related.
From Nancy Rubin Stuart, Author, American Empress: The Life and Times of Marjorie Merriweather Post ( Villard Books, 1995; ASJA PRess, 2003)
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Marjorie Reynolds and Katherine Heigl are not related. Marjorie Reynolds was an American actress known for her roles in classic films such as "Holiday Inn," while Katherine Heigl is a contemporary actress known for her work in television shows like "Grey's Anatomy" and films like "Knocked Up." Despite both being actresses, there is no known familial relationship between the two.
Marjorie Otts's birth name is Marjorie Dawn Clark.
Marjorie Corso's birth name is Todd, Marjorie Dorris.
Marjorie Clark was born in 1909.