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The one gene-one polypeptide theory states that for every gene one protein is synthesized n a cell. This theory has lost favor with the discoveries of post-translational modification, protein splicing and epigenetics, all of which support the production of multiple protein products from a single gene.
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What does the one gene-one polypeptide state?
The one gene-one polypeptide hypothesis states that each gene is responsible for producing one specific polypeptide, which is a chain of amino acids that forms a protein. However, this hypothesis has been modified to the one gene-one protein hypothesis because some genes code for non-protein products like RNA molecules.
What is the one gene-one polypeptide hypothesis?
The one gene-one polypeptide hypothesis is an idea in an attempt to fix the one gene-one protein hypothesis (previously one gene-one enzyme hypothesis) after scientists realized that proteins can be made up by more than one polypeptide chain and that each polypeptide chain is specified by its own gene. An example would be a protein like hemoglobin, the oxygen transporting protein of vertebrate blood cells. Hemoglobin is made up of two kinds of polypeptides. Because of the two polypeptide chains, hemoglobin is made up of two genes. While this hypothesis was an improvement, it wasn't entirely true. While the example is true, the fact of the matter is, eukaryotes are much more complex than 1940s (around the time that Tatum and Beadle first came up with the one gene-one enzyme hypothesis ) technology allowed for scientists to understand. There is a step in RNA processing or post-transcriptional modification where parts of the transcribed gene is cut out (the cut out part is called the intron). Because of this mechanism, it is possible for a single gene to create more than 1 polypeptide.
Why was the one gene one protein hypothesis altered to one gene one polypeptide hypothesis?
Because one gene codes for one polypeptide and some proteins are made of more than one polypeptide and stuck together after translation of the genes that code for these polypeptides. Not sure if there ever was a one gene one protein hypothesis or if its just something they teach in schools to avoid overcomplicating things.
Why has beadle and tatoms one gene - one enzyme hypothesis been midified since the presented it in 1940s?
Tatum and Beadle proposed the "one gene one enzyme" theory. One gene code is responsible for the production of a single protein. "One gene one enzyme" is modified to "one gene one polypeptide" because the majority of proteins are composed of multiple polypeptides.
How did beadle and tatum's research result in the one gene-one polypeptide hypothesis?
The major breakthrough in demonstrating the relationship between genes and proteins came in the 1940s. American geneticists George Beadle and Edward Tatum worked with the orange bread mold Neurospora crassa. Beadle and Tatum studied mutant strains of the mold that were unable to grow on the usual nutrient medium. Each of these mutant strains turned out to lack a single enzyme needed to produce some molecule the mold needed, such as a vitamin or an amino acid. Beadle and Tatum also showed that each mutant was defective in a single gene. Their research led them to propose the "one gene-one enzyme" hypothesis. This hypothesis states that the function of an individual gene is to dictate the production of a specific enzyme.Since then, scientists have learned that some genes actually dictate the production of a single polypeptide, which may make up part of an enzyme or another kind of protein. Beadle and Tatum's hypothesis is now generally stated as one gene-one polypeptide.
What does the one gene-one polypeptide state?
The one gene-one polypeptide hypothesis states that each gene is responsible for producing one specific polypeptide, which is a chain of amino acids that forms a protein. However, this hypothesis has been modified to the one gene-one protein hypothesis because some genes code for non-protein products like RNA molecules.
Relationship between one gene and one polypeptide?
One gene codes for (or provides the recipe) for the creation of one polypeptide through transcription and translation.
What is the job of a gene?
A gene codes for one type of polypeptide (protein).
What is the one gene-one polypeptide hypothesis?
The one gene-one polypeptide hypothesis is an idea in an attempt to fix the one gene-one protein hypothesis (previously one gene-one enzyme hypothesis) after scientists realized that proteins can be made up by more than one polypeptide chain and that each polypeptide chain is specified by its own gene. An example would be a protein like hemoglobin, the oxygen transporting protein of vertebrate blood cells. Hemoglobin is made up of two kinds of polypeptides. Because of the two polypeptide chains, hemoglobin is made up of two genes. While this hypothesis was an improvement, it wasn't entirely true. While the example is true, the fact of the matter is, eukaryotes are much more complex than 1940s (around the time that Tatum and Beadle first came up with the one gene-one enzyme hypothesis ) technology allowed for scientists to understand. There is a step in RNA processing or post-transcriptional modification where parts of the transcribed gene is cut out (the cut out part is called the intron). Because of this mechanism, it is possible for a single gene to create more than 1 polypeptide.
Why was the one gene one protein hypothesis altered to one gene one polypeptide hypothesis?
Because one gene codes for one polypeptide and some proteins are made of more than one polypeptide and stuck together after translation of the genes that code for these polypeptides. Not sure if there ever was a one gene one protein hypothesis or if its just something they teach in schools to avoid overcomplicating things.
Why has beadle and tatoms one gene - one enzyme hypothesis been midified since the presented it in 1940s?
Tatum and Beadle proposed the "one gene one enzyme" theory. One gene code is responsible for the production of a single protein. "One gene one enzyme" is modified to "one gene one polypeptide" because the majority of proteins are composed of multiple polypeptides.
The one gene one polypeptide hypothesis is the currently accepted hypothesis explaining how genes help to determine the phenotype of an organism?
The one gene one polypeptide hypothesis posits that each gene in our DNA encodes for a specific polypeptide or protein. Each protein plays a role in determining the traits or characteristics of an organism. This hypothesis helps in understanding how genetic information is transferred from DNA to proteins, which are key players in determining an organism's phenotype.
What is the DNA segment that carries information for building one protein or polypeptide chain called?
mRNA ( it is like DNA only it is one sided and the t is replaced with a u)
How did beadle and tatum's research result in the one gene-one polypeptide hypothesis?
The major breakthrough in demonstrating the relationship between genes and proteins came in the 1940s. American geneticists George Beadle and Edward Tatum worked with the orange bread mold Neurospora crassa. Beadle and Tatum studied mutant strains of the mold that were unable to grow on the usual nutrient medium. Each of these mutant strains turned out to lack a single enzyme needed to produce some molecule the mold needed, such as a vitamin or an amino acid. Beadle and Tatum also showed that each mutant was defective in a single gene. Their research led them to propose the "one gene-one enzyme" hypothesis. This hypothesis states that the function of an individual gene is to dictate the production of a specific enzyme.Since then, scientists have learned that some genes actually dictate the production of a single polypeptide, which may make up part of an enzyme or another kind of protein. Beadle and Tatum's hypothesis is now generally stated as one gene-one polypeptide.
Which answer best explains why the discovery of alternative splicing forced biologists to change their definition of a gene?
It showed that a gene can direct the production of more than one polypeptide or RNA.
What do gene codes do?
Genes are the code for forming proteins. DNA is formed by nucleotides (adenine, thymine, guanine and cytosine). Every 3 of these bases (along the whole DNA strand), codify for a aminoacid, and several aminoacids form proteins. Several proteins determine a feature. In human genetics, everything except blood type (A, B, AB or 0) is determined by more than one gene.a gene codes for a polypeptide. however recent research shows that a gene doesn't always code for a protein and a gene can result in more than one polypeptide. but for the most part a gene codes for a polypeptide.
What is the theory the synthesis of each enzyme is catalyzed by one specific gene?
The theory you are referring to is the "one gene-one enzyme" hypothesis proposed by Beadle and Tatum in the 1940s. This theory suggested that each gene is responsible for encoding a specific enzyme, which catalyzes a specific biochemical reaction in an organism. Although it has been modified over time, the concept remains fundamental to our understanding of how genes encode proteins and their functions in cells.
