0
The one gene-one polypeptide theory states that for every gene one protein is synthesized n a cell. This theory has lost favor with the discoveries of post-translational modification, protein splicing and epigenetics, all of which support the production of multiple protein products from a single gene.
Still curious? Ask our experts.
Chat with our AI personalities
Blake
Devin
JudyThe one gene one polypeptide theory states that each gene in an organism is responsible for producing a single polypeptide chain. This theory suggests that each gene carries the information needed to synthesize a specific protein or peptide. However, the theory has been updated to reflect that not all genes encode for proteins, but may also produce non-coding RNAs.
Add your answer:
Earn +20 pts
What does the one gene-one polypeptide state?
The one gene-one polypeptide hypothesis states that each gene is responsible for producing one specific polypeptide, which is a chain of amino acids that forms a protein. However, this hypothesis has been modified to the one gene-one protein hypothesis because some genes code for non-protein products like RNA molecules.
What is the one gene-one polypeptide hypothesis?
The one gene-one polypeptide hypothesis states that each gene in the DNA encodes for a single polypeptide (protein). This hypothesis has been updated to the one gene-one protein concept, as some genes can code for proteins that are composed of multiple polypeptide chains.
Why was the one gene one protein hypothesis altered to one gene one polypeptide hypothesis?
The one gene one protein hypothesis was altered to the one gene one polypeptide hypothesis because it was discovered that not all gene products are proteins. Some genes encode functional RNA molecules instead of proteins, and these RNA molecules have important biological roles. Therefore, the concept was expanded to include all gene products, whether they are proteins or functional RNA molecules.
Why has beadle and tatoms one gene - one enzyme hypothesis been midified since the presented it in 1940s?
Beadle and Tatum's "one gene-one enzyme" hypothesis has been modified since the 1940s because it was later found that not all proteins are enzymes, and that some genes can code for multiple proteins through alternative splicing and post-translational modifications. This led to the updated "one gene-one polypeptide" concept to account for the broader functions of genes in protein synthesis.
How did beadle and tatum's research result in the one gene-one polypeptide hypothesis?
The major breakthrough in demonstrating the relationship between genes and proteins came in the 1940s. American geneticists George Beadle and Edward Tatum worked with the orange bread mold Neurospora crassa. Beadle and Tatum studied mutant strains of the mold that were unable to grow on the usual nutrient medium. Each of these mutant strains turned out to lack a single enzyme needed to produce some molecule the mold needed, such as a vitamin or an amino acid. Beadle and Tatum also showed that each mutant was defective in a single gene. Their research led them to propose the "one gene-one enzyme" hypothesis. This hypothesis states that the function of an individual gene is to dictate the production of a specific enzyme.Since then, scientists have learned that some genes actually dictate the production of a single polypeptide, which may make up part of an enzyme or another kind of protein. Beadle and Tatum's hypothesis is now generally stated as one gene-one polypeptide.
