Healing process. Right after phagocytosis.
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Granulation is caused by an excessive release of inflammatory mediators, such as cytokines, which results in the formation of granulation tissue. Factors like chronic inflammation, repeated injury, or persistent infection can trigger this process. Granulation tissue is part of the normal wound healing response but can become excessive under certain conditions.
The term used to describe small knotlike swellings of granulation tissue in the epidermis is "papilloma." These are typically benign and can be caused by various factors such as infections, irritations, or genetic factors. Treatment may involve removal if necessary for cosmetic or functional reasons.
Granulation tissue provides a framework for new blood vessels and collagen production, which are essential for wound healing. It also helps to protect the wound from infection and promotes the migration of cells that are involved in the healing process. Ultimately, the presence of granulation tissue helps to facilitate the formation of new tissue and the closing of the wound.
Granulation tissue is produced during the wound healing process in response to tissue injury or inflammation. It is mainly composed of new blood vessels, fibroblasts, and extracellular matrix components such as collagen. They help to fill in the wound bed, promote tissue repair, and ultimately lead to the formation of scar tissue.
Granulation tissue is characterised by the presence of new blood vessels, fibroblasts and mononuclear cells in an edemateous extracellular matrix. A granuloma is a specific form of chronic inflammation characterised by the prescence of epitheloid macrophages and giant cells (either foreign body giant cells or Langerhaan giant cells) surrounded by a collar of fibroblasts and lymphocytes. Central necrosis may or may not be present.
She had caused the reaction in the animals heart that night.