Wet/damp/faulty ignition wires, contaminated fuel (water), worn out spark plugs.
No, but bad spark plugs or plug wires sure can.
Your 1996 Pontiac Grand Prix will experience cylinder misfires when one or several of the spark plug wires are bad. A bad spark plug can also cause the problem.
POSSIBILITIES: Faulty spark plug - faulty ignition wire - distributor rotor needs replacing - distributor needs replacing. The most common cause of multiple misfires on the B20 / P75 engine used in the 1999 CRV is valve recession. this is a well documented problem on these engines. Repair usually requires replacement of the head.
incorrect engine timing so that it misfires
Several things can cause a Multiple Cylinder Misfire. First and most obvious are your spark plugs and wires. If they havent been changed within the last year that you can remember its time to change them. Faulty Crankshaft sensor would also cause this to happen but is unlikely.
Mechanical issue, ammunition issue.
Wiring and internal engine problems can cause misfires.
P1399 is a pending code for random or multiple cylinder misfires.
In theory, it could, but in all practicality, it would not. The four main causes of misfires are faulty sparkplugs, bad spark plug wires, bad fuel injectors or a loss of compression.
The distributor cap of an ignition system is one possible cause of many for misfires. Other possible sources to investigate are the distributors cap and gears. The flow chart of diagnosing misfires also include the coil, capacitor (if applicable), ignition wires and the spark plugs.
If you're only getting a lean indicator and no other problems you might have a vacuum leak or possibly a problem with the EGR valve. The multiple misfires (assuming P0300 or specific cylinders, P0301 ~ P0306) sound like lack of fuel to the injectors causing misfires, also resulting in O2 sensors "sensing" lean mixtures as a result.