Could be a number of things. Is the noise coming from your transmission, your rear differential, one of the wheels? From the wheels it could be a warped rotor or a wheel bearing failing.
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There are many possibilities from minor to serious. Take it to a trusted mechanic for diagnoses.
Bad head gasket? Cracked Head? CRacked block?
Friction in the transmission system may cause whining noise when a car is accelerating. A poor engine or clutch assembly may cause the excess friction in the transmission system.
It sounds like a CV axle shaft has come loose from the transaxle. This is usually caused by an improperly installed axle shaft of missing or damaged snap-ring type retainer.
Dirty or loose connections or a bad starter.
if the car is rear wheel drive, sounds like a u-joint. If it is front wheel drive, sounds like a cv joint. It could also be your engine mounts wearing out. If the rubber insulation has worn out then the engine will shift slightly against the mount and make a clunking noise. This happened on my 96 Nissan Quest minivan.