The Left Ventricle has the thickest walls! The left ventricular myocardium is much thicker then the right ventricular myocardium because the left ventricle pumps blood into the aorta which takes blood to the rest of the body. (larger pressure gradient)
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Right ventricals
The left ventricle, it works the hardest and needs the most muscle mass.
The left ventricle, being responsible for pumping the blood through the systemic circulation, generates the highest pressures. For this reason, the left ventricle has the thickest muscular walls.
The myocardium is located between the endocardium and the visceral layer of the serous membrane (epicardium) of the heart.
myocardium