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That is a very individual answer. Because injectable Depo is long acting (used as a Birth Control method, it is given every 12 weeks), there is a certain "accumulation" that occurs overtime. Many women who desire conception after using Depo for 2 years or longer, may expect delay in conception. Professionally, I have seen women who have been on Depo for two years or longer who have been unable to conceive for 18-24 months after the Depo was stopped. Again, this is variable. In addition to delayed conception after using Depo, women need to know about the black box warning for Depo. Depo can have a significant negative impact on a women's bone density. It is recommended that a women take calcium and vitamin D supplements daily while on Depo. It is also advised that after 2 years on Depo, the women take a break from the Depo and use an alternative form of birth control for a 3 month period. A bone density scan to evaluate a woman's bone density after two years on the product is also recommended in order to determine bone health before resuming Depo.

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Q: You have been on the depo shot for almost 2 years but you are not taking your next shot and you were wondering when your period would come?
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