The one gene-one polypeptide theory states that for every gene one protein is synthesized n a cell. This theory has lost favor with the discoveries of post-translational modification, protein splicing and epigenetics, all of which support the production of multiple protein products from a single gene.
What does the "one gene-one polypeptide" theory state?
Because one gene codes for one polypeptide and some proteins are made of more than one polypeptide and stuck together after translation of the genes that code for these polypeptides. Not sure if there ever was a one gene one protein hypothesis or if its just something they teach in schools to avoid overcomplicating things.
Tatum and Beadle proposed the "one gene one enzyme" theory. One gene code is responsible for the production of a single protein. "One gene one enzyme" is modified to "one gene one polypeptide" because the majority of proteins are composed of multiple polypeptides.
enzyme enzyme is right but it has been modified to polypeptide
Alternative splicing permits a single gene to code for more than one polypeptide. In alternative splicing, certain exons of a gene may be included or excluded from the messenger RNA used to code for proteins.
What does the "one gene-one polypeptide" theory state?
One gene codes for (or provides the recipe) for the creation of one polypeptide through transcription and translation.
A gene codes for one type of polypeptide (protein).
Because one gene codes for one polypeptide and some proteins are made of more than one polypeptide and stuck together after translation of the genes that code for these polypeptides. Not sure if there ever was a one gene one protein hypothesis or if its just something they teach in schools to avoid overcomplicating things.
Tatum and Beadle proposed the "one gene one enzyme" theory. One gene code is responsible for the production of a single protein. "One gene one enzyme" is modified to "one gene one polypeptide" because the majority of proteins are composed of multiple polypeptides.
enzyme enzyme is right but it has been modified to polypeptide
Alternative splicing permits a single gene to code for more than one polypeptide. In alternative splicing, certain exons of a gene may be included or excluded from the messenger RNA used to code for proteins.
One gene one enzyme theory
The one gene-one polypeptide hypothesis is an idea in an attempt to fix the one gene-one protein hypothesis (previously one gene-one enzyme hypothesis) after scientists realized that proteins can be made up by more than one polypeptide chain and that each polypeptide chain is specified by its own gene. An example would be a protein like hemoglobin, the oxygen transporting protein of vertebrate blood cells. Hemoglobin is made up of two kinds of polypeptides. Because of the two polypeptide chains, hemoglobin is made up of two genes. While this hypothesis was an improvement, it wasn't entirely true. While the example is true, the fact of the matter is, eukaryotes are much more complex than 1940s (around the time that Tatum and Beadle first came up with the one gene-one enzyme hypothesis ) technology allowed for scientists to understand. There is a step in RNA processing or post-transcriptional modification where parts of the transcribed gene is cut out (the cut out part is called the intron). Because of this mechanism, it is possible for a single gene to create more than 1 polypeptide.
mRNA ( it is like DNA only it is one sided and the t is replaced with a u)
True
It showed that a gene can direct the production of more than one polypeptide or RNA.