Carlisle's father was a preacher that looked for "creatures from hell" around 1600, to kill them. But his father never found a real creature, and many died not being really guilty.
When his father died, Carlisle assumed his positions, and he finally found a real cove of vampires. Carlisle and his group tried to kill them, but when Carlisle got near him the vampire struck and that's how Carlisle was turned into a vampire
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Carlisle was a son of a famous exsploer,who tracked down vampires/werewolfs/witches things like that, then one day carlisle found a cave underground of vampires,so carlisle got a group of people from the town near by, to go kill the vampires. But because the vampires were underground so long, the vampires started to attack the mob. One of them attack carlisle,then the vampires left him there bleeding in the gutters while the vampires ate some of the mob.
A few days later,when carlisle woke up, he couldent belive what he became, a vampire. He tried killing him self,which is not easy for a new-born vampire. So he hid behind a sack of rotting potatos and stayed there for a cople of weeks. But when he started to get thirsty, he didnt want to kill humans,so he lived on animal blood.
Because carlisle was very lonley, after a few 100 years,he became a doctor so he could help people. Then he found a teenager called edward who was dieing in a hospital of a flu,so carlisle turned edward into a vampire to save him. Then he created Esme his wife because she loved carlisle, then it was rosealie and emment, then Alice and japser. So now they are the big Cullen faimly.
Carlisle Cullen was born in 1643, and was changed into a vampire in 1666, when he was 23.
He was bitten one night when he was out chasing one with other people. He holed up in a cellar of some kind during the transformation.
Carlisle was turned into a vampire by a vampire named Edward after he was on the brink of death due to a severe illness. Edward changed Carlisle in order to save his life.