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The poison in a Pyracantha is in such tiny amounts that being pricked by a thorn would not cause any problems.

The above may be true but I have found on several occasions when pruning our Pyracantha that the almost inevitable pricks by the amazingly sharp thorns will often leave me with a very sore and red finger or arm. This goes away after 2 or 3 days. This is possibly due to the minute amounts of cyanide in the plants.

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Q: If poked by a Pyracantha thorn is it poisonous?
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