Safari is available for Mac OS X and Windows, not including a special version for the iPhone OS. Opera is available for Mac OS X, Windows, Linux, FreeBSD, BeOS, Solaris, OS/2 Warp, and QNX. It also has special versions available for most cellphones and PDAs, the Wii, and the Nintendo DS/DSi.
Safari is based on the Open Source WebKit / KHTML rendering engine (also used in Konqueror, Chrome, the Android Browser, and many other browsers). Opera uses it's own proprietary rendering engine, Presto. Opera has been available for much longer than Safari, and was the pioneer for many web features now considered standard, such as tabs. Safari is a stand-alone web browser (with RSS capabilities), while Opera is a full-featured internet suite, featuring, apart from the web browser, an email client, chat client, torrent downloader, web compressor, syncing service, etc.
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An operetta is a type of light opera. An opera-bouffe is a special type of operetta that was specifically introduced by Jacques Offenbach.
Opera Seria is a serious or tragic opera, and Opera Buffa is a comic opera. Other than that there are more differences between operas of different periods than between the serious and the comic operas.
The key difference between the 2 browsers is the engine that they are built upon. Opera 12 uses Opera's own Presto engine, whereas Opera 17 uses the Chromium engine that underlies Google's Chrome Browser. Opera has also declared that they would follow Google when they use the Blink fork of the Webkit engine.
The main reason is that The Phantom of the Opera is an opera while The Entertainer is a musical. I hoped this helped. :)
An opera is a composition, with music and text. The same opera may be performed anywhere. Any differences will be in the production values, not in the operas themselves.