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Yes, Tylenol will help ease the pain of menstrual cramps - all non-steroidal anti-inflammatory drugs all work on menstrual cramps as it is inflammation caused by hormones that cause uterine contraction which cause menstrual cramps. It is however far better to prevent yourself from getting menstrual cramps to begin with, often lifestyle changes alone are enough to prevent menstrual cramps.

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Q: Would tylenol help for period cramps?
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