Africans and Europeans shared immunities to Old World diseases. Its easier to make someone a slave outside of their home.
They tried to enslave the Native Americas but this being there land, used it to there advantage and fought back, making it more trouble then it was worth. Europe was already taking slaves from Africa so the America settlers started going there also, tribes in Africa that where fighting with one another would help the Europeans and American round up people from there enemies tribe.
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Africans were enslaved instead of Native Americans in early American history because Native Americans were more vulnerable to diseases brought by Europeans and had more established territories that made permanent enslavement difficult. Additionally, Europeans justified the enslavement of Africans by claiming they were racially inferior, which did not apply to Native Americans in the same way.
Europeans used Africans as slaves in the West Indies for several reasons, including resistance by Native Americans, higher immunity of Africans to diseases, cultural differences, and the availability of Africans through the transatlantic slave trade. Native Americans were also more likely to escape due to their knowledge of the land.
African laborers often had more experience with agriculture than American indigenous peoples.
Enslaved Africans looked upon the branding iron with horror, as it symbolized the dehumanizing process of being marked as property by their captors. This physical act reinforced their status as objects to be owned and traded, rather than as human beings with dignity and autonomy.
The high mortality rates among indigenous populations due to diseases brought by Europeans led to the shift towards African labor on plantations. Africans were also seen as a more reliable source of labor due to their perceived immunity to certain diseases and experience with agriculture. Additionally, the Atlantic slave trade provided a large supply of enslaved Africans for labor in the Americas.
African tribes participated in the transatlantic slave trade by capturing and selling individuals from rival tribes as slaves to European slave traders. Some tribes also profited from the trade by serving as middlemen for European slave traders. However, it's important to note that the majority of Africans enslaved and sent to the Americas were captured and sold by Europeans, rather than by their fellow Africans.