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Because a hormone testosterone secreted only in males is also responsible for stimulation of hormone erythropoetin secreted from kidneys. Erythropoetin is responsible for synthesis of rbcs. So males have higher hematocrit than that of females.

Women have estrogen! It is a natural inhibitor of erythropoitin (a hormone secreted by the kidneys to erythropoiesis in the bone marrow), on the other hand, testosterone is an activator.

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Q: Why is there a difference between men and women hematocrit level?
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