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its only containdicated in the first trimester of pregnancy and in breast feeding
why its contraindicated in first trimester pregnancy: it crosses the placenta, in animal drug trials this had no effect on mice at 5x the normal dose, however it had a statistically significant increased mortality in human pregnant females, due to this the study was stopped and never completed, it is unknown why this occurs in humans
why its contraindicated in breast feeding: it gets in to breast milk and causes increased tumors
currently the only indication i know of for metronidazole in pregnancy is trichomniasis infection, which even if caught during first trimester, shouldnt be treated until at least the second trimester
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