tattoo pigment is typically made from different minerals and ores. depending on what the collor is it it possible that the persons body would reject the ink just like any other foreign matterial being put into your body. soemtimes this just causes certain collors to take longer to heal but some people, i know from first hand experience, completely reject certain collors. red just happens to be the most common collor for people to have problems with which is why its usually recommended, but very rairly actually done, that you get a collor test done somewhere hidden to make sure you don't get a reaction to any of the collors that you are planning to use.
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