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drug abuse could lead to drug addiction and dependence

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Drug abuse, drug addiction, and drug dependence all involve the misuse of drugs, leading to negative consequences for the individual's health and well-being. They are all characterized by a compulsive need to use drugs despite knowing the harm they cause. Additionally, they often require professional treatment to address underlying issues and achieve recovery.

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Q: What is the same about drug abuse drug addiction and drug dependence?
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Continue Learning about Chemistry

The body's need for larger and larger amounts of a drug to produce the same effect?

This describes tolerance, which occurs when the body adapts to a drug so that larger doses are needed to achieve the same effects as initial use. Tolerance can lead to dangerous levels of drug consumption and can contribute to the development of dependence and addiction. Regularly increasing drug doses without medical guidance can be harmful to physical and mental health.


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A drug molecule that is lipophilic (capable of easily crossing the blood-brain barrier) and activates the brain's reward system by stimulating the release of dopamine is more likely to be addictive. If the drug rapidly enters the bloodstream and has a short duration of action, it may also increase the likelihood of addiction by causing intense and immediate reinforcement of drug-taking behavior. Additionally, if the drug induces tolerance or physical dependence, it can lead to addictive behavior as the individual requires higher doses to achieve the same effects and experiences withdrawal symptoms upon cessation of the drug.


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Physical dependence on a substance occurs when the body adapts to the presence of that substance and requires it to function normally. This can result from repeated use of certain drugs, causing changes in the brain and body that lead to withdrawal symptoms when the substance is not present.


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