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There are many to choose from, depending on your criteria:

1- Desert Eagle .50AE

2. .44 Magnum

3. 10mm

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Wiki User

9y ago
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Anonymous

Lvl 1
4y ago
What about magnum research 500 magnum?
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Jay Breezy

Lvl 2
3y ago

Currently the Smith and Wesson 500 S&W Magnum. However the 460 S&W although smaller and lighter is much faster with much more range and accuracy especially with a good scope(deer at 300 yards!).

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Q: What is the most powerful handgun in US?
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Related questions

Do you have a picture of the most powerful handgun in the world?

No


The picture of the most powerful handgun in the world?

Unknown


Is a S and W 357 magnum a good handgun?

A VERY good handgun- for most puposes. Durable, reliable, accurate, and powerful.


What is the most powerful handgun bullet?

Probably, almost certainly, the .600 Nitro Express is the overall most power handgun bullet. Let me alter this answer by saying the .600 Nitro Express is a rifle round that one company made a pistol for. The most powerful handgun cartridge is the 500 S&W Magnum.


How does 44 mag hand gun rate for most powerful hand gun?

Not even close. There are several more powerful handgun cartridges, not counting the single shot pistols that use rifle cartridges. While Dirty Harry may have proclaimed it to be "The most powerful handgun in the world"- it is not.


What is the most powerful handgun caliber in the world besides the 44 mag?

There are many handgun rounds that exceed the 44 mag. 454, 460, 500 to name a few.


What is the most powerful handgun?

Fairly certain it is the Thompson Contender .600 Nitro Express for production firearms.


What is the most powerful 22 handgun?

Can't be answered withou knowing if you are referring to a rimfire or centerfire 22


Is a 9 mm the most powerful handgun?

No, not by a longshot (no pun intended). Almost all "major" caliber handguns are more powerful than the 9mm.


What was the most powerful gun of the old west?

Rifle, shotgun, or handgun? The 10 gauge shotgun at close range would be very high on the list, as would some of the buffalo rifle cartridges, such as the 45-110. The .45 Colt revolver was possibly the most powerful handgun of the day.


How do you use magnum in a sentence?

The .500 S&W magnum is the most powerful handgun round commercially available.


What kind of handgun was used in the film dirty harry?

Dirty Harry used a 44 Magnum in his words "The most powerful handgun in the world." Specifically, it was a Smith and Wesson Model 29 in a .44 magnum. In addition, it is not the most powerful handgun in the world (not even at the time of filming.)