While this will vary somewhat based on differences in rifles and loading of the cartridge. However, the biggest factor will be what USE you plan to make of the .270.
For deer, up to 400 yds, depending on skill of the shooter. For elk or bear, about 250 yds. Those are the ranges at which the .270 will deliver enough energy to insure a clean kill of the game animal (if you do your part). If you are shooting paper (target shooting) the .270 is capable of good accuracy at the 800 yard line- or further.
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