dATP, dTTP, dGTP, dCTP
Base
DNA polymerase consists of two parts - "DNA" which stands for deoxyribonucleic acid, the molecule that carries genetic information, and "polymerase" which refers to the enzyme that helps to build DNA by assembling nucleotides in the correct sequence during DNA replication. In summary, DNA polymerase is the enzyme responsible for synthesizing new DNA strands by adding nucleotides in a complementary manner to an existing DNA template strand.
Nucleic acids are made up of smaller units called nucleotides. Each nucleotide consists of a sugar molecule (ribose or deoxyribose), a phosphate group, and a nitrogenous base (adenine, guanine, cytosine, thymine, or uracil). These nucleotides join together through phosphodiester bonds to form the backbone of DNA and RNA molecules.
The molecule that supplies the energy for polymerization of nucleotides in transcription is called adenosine triphosphate (ATP). During transcription, ATP is hydrolyzed to adenosine diphosphate (ADP) and inorganic phosphate (P_i), releasing energy that drives the formation of phosphodiester bonds between nucleotides to form RNA.
A nucleotide is made of 3 parts: Sugar, Phosphate group and Base RNA and DNA have different sugars and different bases. 1. Sugar DNA - Deoxyribonucleic acid has the sugar deoxyribose RNA - Ribonucleic acid has the sugar ribose In RNA, the sugar has an extra oxygen. In DNA, the oxygen is not there. 2. Bases DNA has Adenine, Thymine, Guanine, and Cytosine. A pairs with T and C pairs with G. In RNA, Uracil replaces Thymine. So A pairs with U and C still pairs with G. more here: http://en.wikipedia.org/wiki/Rna#Comparison_with_DNA DNA nucleotides: http://en.wikipedia.org/wiki/Image:DNA_chemical_structure.svg RNA nucleotide: http://en.wikipedia.org/wiki/Image:RNA_chemical_structure.GIF
deoxythymidinetriphosphate (dTTP) is the nucleotide in DNA that is not present in RNA. The corresponding base is thymine (T). RNA contains the nucleotide uridinetriphosphate (UTP) instead. In their incorporated forms, the will be in the monophosphate state.Note: Someone previously changed this to read "Deoxythymine is the nucleotide in DNA that is not present in RNA. The corresponding Rna base is Uracil." While they had good intentions, this represents several common errors in molecular Biology. "Deoxythymine" does not exist as a nucleotide (or anything at all for that matter). The nucleoside is called deoxythymidine. If a nucleoside such as deoxythymidine is paired with one or more phosphate groups, it is then a nucleotide.
dUTPase is an enzyme that helps maintain the balance of nucleotide pools in the cell by cleaving dUTP to dUMP and inorganic pyrophosphate. This helps prevent the incorporation of uracil into DNA, which could lead to mutations and DNA damage. Additionally, dUTPase is involved in regulating the levels of dTTP, an essential nucleotide for DNA synthesis.