Difference is action on AV 1 and AV 2 receptors.
One study showed that Valsartan is more effective than olmesartan add on therapy on patient on Amlodipine and developed ankel oedema.
It is observed that there is singnificent secondary activation of RAAS after olmesartan.
Although in general the BP lowering effect more with olmesratan.
Valsartan is the generic of a blood pressure medication sold as Diovan.
Valsartan is the generic of a blood pressure medication sold as Diovan.
olmesartan
valsartan
telmisartan lowered both systolic and diastolic BP to a greater extent than did valsartan
Telmisartan has proven mortality benefits in patients at high risk of cardiovascular events, regardless of blood pressure drops (see ONTARGET trial)Telmisartan and olmesartan are indicated for use in patients with hypertension, and telmisartan has an additional indication for the prevention of cardiovascular morbidity and mortality in patients over 55 years with- coronary artery disease- peripheral artery disease- previous stroke- previous TIA- high risk diabetes with evidence of end-organ damage, such as renal (see approved TGA indications)Olmesartan does not have any additional indications.Telmisartan has sustained blood pressure lowering effects, which last for up to 48 hours (see Product Information)Telmisartan has a longer half-life than olmesartan (see Product Information)Telmisartan has the lowest renal clearance, olmesartan is contraindicated in patients with severe renal impairment (see Product Information)ROADMAP Study with olmesartan raised concerns of increased myocardial infarcts, theorised to be due to the quick onset of action (see ROADMAP trial)
Olmesartan medoxomil hidrolyzed dissolved
Olmesartan have higher binding affinity to AT1 receptor. As the molecule has lighter group, the dissociation with AT1 receptor is significantly lower when compared to Telmisartan.
is Losarten a subsitute for telmisartan
no
According to clinical research only 0.9% of patients taking olmesartan have cough compared to placebo 0.7% group (no drugs), but my dad developed cough after taking olmesartan. He had earlier taken Ramipril prescribed by a cardiologist, who did not inform him of the notorious side effect of cough.He suffered for 2 months thinking is viral flu.
No. Benazepril is an "ACE inhibitor" (angiotensin converting enzyme inhibitor). Diovan is an "angiotensin receptor blocker" (ARB). These two classes of medications are related in that they lower blood pressure by blocking the RAAS (renin-angiotensin-aldosterone system). The brand name of benazepril is Lotensin. The generic name for Diovan is valsartan.