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What is the difference between the lock and key model versus the induced fit model of the enzyme substrate complex?
Wiki User
∙ 14y ago
The lock and key model means that the substrate must perfectly fit the enzyme, and the enzyme does not change. The induced fit model is different as when the substrate fits together with the enzyme, the enzyme itself will change to either join substrates together or break a substrate down.
Wiki User
∙ 14y ago
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How can induced fit influence the specificity of an enzyme?
Induced fit: is a more recent theory which suggests that the substrate attaches to the enzyme in a relatively accurate fit, then the enzyme moulds around it, then continues the chemically complex reaction. Lock and Key Mechanism: As obvious as the name states, the lock and key model is simply the substrate fitting acutely into the enzyme with no adjustments required to the enzyme. K.G. ;)
What is the meant by the lock and key hypothesis?
The lock is the equivalent to that of an enzyme while the key is portrayed as the substrate. Like an enzyme, the lock can be reused many times as it remains chemically unchanged at the end of the reaction. Also, the fact that reactions occur only at the active site, or binding site, is showed as the key only being able to open the lock only at the keyhole, not anywhere else. The hypothesis also shows the fact that enzymes can only catalyse a specific substrate, showed as the lock, only being able to open with a specific key. Firstly,the substrate will enter the active side of the enzyme.then,the enzyme will change it shape slightly as the substrate binds.During this time,the substrate will be broken down.After that,the product will leave the active sides of the enzyme.
What type of intermolecular forces are expected between CH3CH2CHO molecules?
dipole forces and induced dipole forces
Do London dispersion forces exist between polar molecules and result from temporary dipoles?
London dispersion forces derive from the interraction of instantaneous induced dipoles - the inetraction of polar molecules (having a permanent dipole )is called a Keesom force- the force between a permanent polar molecule and an induced dipole in another molecule is called a debye force--
What type of intermolecular force is common to xenon and methanol?
London Disperson Forces (or Induced Dipole - Induced Dipole)
Define the enzyme-substrate complex?
The theory of enzyme-substrate complex was established by Michaelis and Menton in 1913.According to their theory,enzyme combines with substrate to form enzyme-substrate complex.The transient complex has a lower energy of activation than that of substrate alone.This results in the acceleration of the reaction.The enzyme-substrate complex is broken down into enzyme and products of the reaction. E+S -ES - - -ES - - -E+P The different hypotheses of enzyme-substrate complex formation have been postulated.Early theory was postulated by Emil Fischer.According to this theory,the catalytic site of enzyme is preshaped to fit of the substrate.This hypothesis is called "lock and key" or rigid template.The next hypothesis has been proposed by Koshland in the late 1950s.The hypothesis was called "induced fit".Acccording to this theory,a catalytically active configuration of enzyme molecule and that of the active site can be induced only at the moment of attachment of the substate molecule,that is the substrate induces a conformotional change in the enzyme. At the present time,model of "induced fit" is modified.Binding the substrate with the enzyme leads not only to the conformational change of the protein molecule,but also to a geometrical and electrontopographic rearrangement of the substrate molecules. The modern "induced fit" hypothesis presumes the existence between the enzyme and the substrate of not only spatial or geometrical complementarity,but also electrostatic charge complementarity.
What is a change in the shape of an enzyme allowing it to react effectively with a substrate is a what?
An induced fit is a change in the shape of an enzyme which allows it to react effectively with a substrate. The reason for the alteration is to speed up a chemical reaction.
What is the Mode of action of enzymes in terms of substrate complex?
These are the modes: 1. Lock and Key hypothesis 2. Induced Fit Hypothesis
What is a induced fit hypothesis?
a. The substrate can be altered so it is induced to fit into the enzyme's active site. b. The enzyme changes its shape slightly as it binds to the substrate. c. The enzyme is altered so it is induced to fit many different types of substrate. d. Several sites on an enzyme can be induced to act on a substrate.
How the lock and key model and the induced fit model differ?
According to lock and key model both the enzymes and the substrate possess specific geometrical shapes that fit exactly into one another. WHILE According to the induced fit model enzymes are more flexible structures and their active site is reshaped as substrate interacts with the enzymes.
Enzymes that are produced only when substrate is present are termed?
induced enzyme
How does an enzyme recognize its substrate?
On one part of an enzyme is an active site (which is what the substrate binds to) that is shaped a certain way, say a triangle. A substrate that's in the shape of a square won't fit onto the triangle/the enzyme - but a substrate that has an indent in the shape of a triangle will. The way an enzyme recognizes its substrate is if it can attach itself to the enzyme's active site.
What is the difference between impressed voltage and induced voltage?
A: impressed voltage is a mechanical connection involved induced has no mechanical connection except for proximity
As an enzyme fits into a substrate at the active site it undergoes a slight change in order to fit into the substrate. this process is defined by a concept called?
This concept is called an induced fit.
This is a modification of the lock and key model that suggests the active site of an enzyme is continually reshaped by interactions with the substrate until the substrate is completely bound and the c?
induced fit
How can induced fit influence the specificity of an enzyme?
Induced fit: is a more recent theory which suggests that the substrate attaches to the enzyme in a relatively accurate fit, then the enzyme moulds around it, then continues the chemically complex reaction. Lock and Key Mechanism: As obvious as the name states, the lock and key model is simply the substrate fitting acutely into the enzyme with no adjustments required to the enzyme. K.G. ;)
What is the difference between a spontaneous ovulator and an induced ovulator?
Spontaneous ovulator is like animals that ovulate out of nowhere. Induced ovulator is when animals ovulate because of/after mating like Llamas and cats.
