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A polysome is a group of ribosomes reading a an mRNA transcript in the cytosol not bound to an endoplasmic reticulum whereas a Ribosome is the single structure that could or could not be reading an mRNA transcript at any given time. Free ribosomes tend to hang out on endoplasmic reticulum(ER), making that ER rough, giving it the name rough endoplasmic reticulum. Polysomes also tend to make cytosolic proteins that will usually remain inside of the cell, whereas ribososmes on the RER will make proteins into the leumen of the ER they are bound to...to be futher modified and sent to the Golgi to be packaged and enevtually secreted (sent outside of the cell)

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Ribosome is a single subunit responsible for protein synthesis, while polysome is a cluster of multiple ribosomes bound to the same mRNA strand simultaneously. Polysomes accelerate the rate of protein production compared to individual ribosomes.

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9mo ago
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Q: What is the difference between ribosome and polysome?
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