What is the difference between replicate and duplicate?

Answer 1

To duplicate is to make an exact copy. (Ex. A double. A duplicate copy of the report looks exactly the same as the first.) To replicate is to make a similar copy. (Ex. A replica, or a knock off purse is similar to the real item but not the same)

Answer 2

To duplicate is to make an exact copy of something.

To replicate is to make a close to or exact copy of something.

Replicating gives some leeway and doesn't have to be a perfect copy.