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primary pharmacodynamics (studies to

investigate the designed mode of action

expected to provide the desired clinical

benefit);

secondary pharmacodynamics (studies

designed to explore the broader

pharmacology of a compound e.g. actions not

expected from its primary mode of action that

may arise from additional actions of the

compound);

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βˆ™ 12y ago
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βˆ™ 6mo ago

Primary pharmacodynamics refers to the direct effect a drug has on its target receptor or enzyme to produce a therapeutic response. Secondary pharmacodynamics refers to additional effects that the drug may have on other receptors or enzymes, which may contribute to its overall pharmacological profile or side effects.

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Q: What is the difference between primary and secondary pharmacodynamics?
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