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Local manifestations of inflammation are result of the vascular changes associated with the inflammatory process, including vasodilation and increased capillary permeability. the symptoms include redness, heat, swelling, and pain. While, the principal systemic effects of inflammation are fever and increases in levels of circulating leukocytes (leukocytosis) and plasma proteins (acute-phase reactants).

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Q: What is the difference between local and systemic manifestations?
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