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What is the difference between eudragit RS PO and eudragit RL PO?
Wiki User
∙ 10y ago
Solid substances obtained from EUDRAGIT® RL 100 or EUDRAGIT® RS 100. EUDRAGIT®
RL PO (Type A) and EUDRAGIT® RS PO (Type B) are described in the monographs quoted above.
EUDRAGIT® RL 100 / RL PO and EUDRAGIT® RS 100 / RS PO are copolymers of ethyl
acrylate, methyl methacrylate and a low content of a methacrylic acid ester with quaternary ammonium groups (trimethylammonioethyl methacrylate chloride). The ammonium groups are present as salts and make the polymers permeable. The molar ratio of ethyl acrylate, methyl methacrylate and trimethylammonioethyl methacrylate is approx. 1:2:0.2 in EUDRAGIT RL and approx. 1:2:0.1 in EUDRAGIT RS.
Wiki User
∙ 10y ago
Eudragit RS PO is a cationic polymer, while Eudragit RL PO is an anionic polymer. Eudragit RS PO is typically used for sustained-release formulations due to its permeability characteristics, while Eudragit RL PO is often used for enteric coatings due to its pH-dependent solubility properties.
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In eudragit rl 100 what does rl stand for?
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What has the author Mark Eisei Sugamori written?
Mark Eisei Sugamori has written: 'Viability of islets of Langerhans microencapsulated in eudragit RL 100 for a bioartificial endocrine pancreas'
In polymer eudragit RL100 what 100 means?
] Description: Methacrylate-based coating materials with a variety of functional properties.Functionality Trade name Anionic polymer of methacrylic acid and methacrylates with a -COOH group Eudragit® L 100-55 - powder, spray dried L 30 D-55 which can be reconstituted for targeted delivery in the duodenum Eudragit® L 30 D-55 - aqueous dispersion, pH dependent polymer soluble above pH 5.5 for targeted delivery in the duodenumEudragit® L 100 - powder, pH dependent polymer soluble above pH 6.0 for targeted delivery in the jejunumEudragit® S 100 - powder, pH dependent polymer soluble above pH 7.0 for targeted delivery in the ileum.Eudragit® FS 30 D - aqueous dispersion, pH dependent polymer soluble above pH 7.0, requires no plasticizerCationic polymer with a dimethylaminoethyl ammonium group Eudragit E 100 - granules, pH dependent, soluble in gastric fluid up to 5.0, swellable and permeable above pH 5.0. Eudragit® E PO - powder form of E-100Copolymers of acrylate and methacrylates with quarternary ammonium group. Insoluble, High PermeabilityEudragit® RL 30D - aqueous dispersion, pH independent polymer for sustained release formulationsEudragit® RL PO - powder, pH independent polymer for matrix formulationsEudragit® RL 100 - granules, pH independentInsoluble, Low PermeabilityEudragit® RS 30D - aqueous dispersion, pH independent polymer for sustained release formulationsEudragit® RS PO - powder, pH independent polymer for matrix formulationsEudragit® RS 100 - granules, pH independentCopolymers of acrylate and methacrylates with quarternary ammonium group in combination with sodium carboxymethylcellulose Eudragit RD 100 - powder, pH independent for fast disintegrating films 2) Applications:Enteric Coatings Eudragit® L 100-55 or L 30 D-55 - delivery to the duodenum (pH > 5.0). Exact pH controlled drug release can be adjusted by a combination of polymers and coating thickness. Eudragit® L 100 - delivery to the jejunum (pH > 6.0).Eudragit® S 100 - delivery to the intestine (pH 6.0 to 7.5), site specific drug delivery can be achieved by combining with Eudragit® L types.Eudragit® FS 30 D - delivery to the colon (pH >7.0).Acryl-eze® --one step dry enteric coating system, soluble at pH 5.5Sustained Release Coatings Eudragit® RL and RS - release profile determined by the ratio of RL to RS polymers, and the film thickness applied. Taste Masking Eudragit® RD 100, pH independent, fast disintegrating film Eudragit® E 100 and EPO, pH dependent cationic polymer, soluble in gastric fluid up to pH 5.0, swellable and permeable above pH 5.0Rapidly disintegrating Films Eudragit® RD 100
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