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The conjugated vaccine has a protein that is bound to the polyscharride to enhance its immunogencity. The unconjugated is the polysacharride only which is less imuunogenic.

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13y ago
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5mo ago

Conjugated bilirubin is water-soluble and has undergone processing in the liver to become more easily excreted in bile. Unconjugated bilirubin is insoluble in water and is the form that results from the breakdown of hemoglobin in red blood cells. They differ in terms of solubility and the liver's processing involvement.

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Q: What is the difference between conjugated and unconjugated bilirubin?
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What is the difference between conjugated and unconjugated vaccines?

Conjugate - certain bacteria have polysaccharide outer coats that are poorly immunogenic. By linking these outer coats to proteins (e.g. toxins), the immune system can be led to recognize the polysaccharide as if it were a protein antigen. This approach is used in the Haemophilus influenzae type B vaccine. [Wikipedia]


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