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Calibration Sensitivity(m): slope of acalibration curve at the consentration of interest

y=mx+n

m:slope(Calibration Sensitivity)

x:concentration

n:signal of blank

Analytical Sensitivity: response to noise ratio

A.S=m/S

m:slope

S:standard deviation of the measurement

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12y ago
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6mo ago

Calibration sensitivity refers to the ability of an instrument to accurately detect changes in levels of a sample. Analytical sensitivity refers to the lowest amount of analyte that can be reliably measured by an assay. Calibration sensitivity is related to instrument performance, while analytical sensitivity is specifically related to the assay's detection limit.

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Q: What is the difference between calibration sensitivity and analytical sensitivity?
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