What is the difference between buccal and sublingual absorption?

Answer 1

Buccal absorption refers to the entire mucus membrane of the mouth, whereas sublingual absorption is specific to the heavily vascular area below the tongue, the most rapid and efficient area of administration through the mouth.

Answer 2

Buccal absorption occurs when medication is absorbed through the tissues of the cheek, while sublingual absorption occurs when medication is absorbed under the tongue. Sublingual absorption typically results in faster drug delivery into the bloodstream compared to buccal absorption.