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Beta HCG is a molecule composed of two pieces: alpha and beta HCG.

Free beta only stresses you're talking about a loose beta subunit instead of it assembled into the intact HCG molecule.

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Beta-HCG (human chorionic gonadotropin) is a hormone produced during pregnancy. Free beta-HCG refers to the fraction of beta-HCG that is not bound to other molecules in the blood. Both are used in pregnancy testing, but free beta-HCG may be more specific in certain situations like screening for Down syndrome.

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Q: What is the difference between beta-HCG and free beta-HCG?
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